Baus locus (TYRP1)

Baus locus (TYRP1)

29 Settembre 2021 0

55,00

Gene TYRP1 (Tyrosinase related protein 1) is responsible for chocolate/liver brown colour in dogs. This coat colour is inherited recessively. There are 4 different variants on B locus in Australian Shepherds: bc, bs, bd and baus. Combination of any two recessive alleles will result in chocolate/liver brown colour (for example two bc alleles or one bc and one bs allele). Because TYRP1 gene is related to eumelanin production, it only affects dogs which have genotype E/E or E/e on E locus. B locus also affects colour of the nose, eyes and pads. Dogs with genotype e/e produce only pheomelanin in coat but production of eumelanin in the nose, eyes and pads is not affected and therefore totally controlled by B locus. Depending on genotypes of E and B loci dog can have yellow coat and brown nose/eyes (e/e, b/b) or chocolate coat and brown nose/eyes (E/e or E/E and b/b). Test for B locus in Australian Shepherds consists of four separate tests in order to find the presence of recessive alleles (bc, bs, bd and baus). Results are reported as combined results as well as results for each single allele tested. Se hai già testato il tuo Australian Shepherd per il locus B prima che il baus locus fosse noto, puoi ordinare solo baus test.Quando vengono rilevate due, tre o quattro varianti a copia singola di bc, bd, bs o baus, la presenza di più varianti su un singolo la copia del gene non può essere esclusa. Pertanto, il genotipo complessivo del locus B per un cane potrebbe essere B / bo b / b (il cane può apparire nero o marrone) e non può essere determinato dal laboratorio senza ulteriori test sui genitori.